These latest figures follow a rise in interest rates on 30-year US mortgages to a 14-month high and key equities indexes continuing to slide.
Redemptions from US bond funds were concentrated in high yield, intermediate term and municipal bond funds with mortgage-backed and
long-term corporate funds also seeing significant outflows.
Redemptions from emerging markets bonds and equity funds were the highest since the third quarter of 2011, with combined outflows exceeding $8bn (£5bn, €6bn).
Europe Middle East and Asia equity funds – hit by the impact of the eurozone debt crisis on key markets – also posted their biggest outflow in 80 weeks as investors pulled over $100m out of Russia, emerging Europe regional and Turkey equity funds. The latter, however, did show signs of recovery towards the end of last week after the Turkish Government moved to defuse political protests.
Other markets that experienced fresh outflows included China, Switzerland and Brazil.
There were some inflows to anchor overall flows into Europe – with German regional funds hitting a 51 week high in June as investors bought into predictions that growing exports allied to a general shift towards more stimulatory fiscal policy, will drag the region out of
recession later this year. Japan equity and China bond funds also extended their current inflow streak
Energy and industrial sector funds were the only two of the 11 major groups tracked by EPFR to post inflows greater than $20m. Overall flows into energy funds climbed to a five week high with funds specializing in alternative energy investments faring better than those focused on oil production.